Cytological and Ecological Observations on the Flagellate Transformation of Naegleria gruberi

Further observations on the metaplasia of an amoeba, Naegleria gruberi.

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Some Observations on the Actions of Steroids on the Metaplasia of the Amoeba, Naegleria Gruberi.

Studies of the rhizoplast from Naegleria gruberi.

A procedure utilizing homogenization and centrifugation in a low ionic strength buffer containing Triton X-100, has been used to facilitate the isolation of the rhizoplast from flagellates of Naegleria gruberi. This has enabled a study to be made of the physical and biochemical properties of this organelle. The rhizoplast is shown to be a proteinaceous structure with chemical properties similar...

Calcium regulation of flagellation in Naegleria gruberi.

The amoeba-to-flagellate transformation of Naegleria gruberi was studied, exploring the role of calcium in control of this pattern of morphogenesis. A direct and an indirect role for calcium are postulated based on experimental results. Direct inhibition in the presence of calcium is caused by ionophore A23187, substances with ionophore-like activity (amphotericin) and the hormone calcitonin, w...

A Nonmitochondrial Hydrogen Production in Naegleria gruberi

Naegleria gruberi is a free-living heterotrophic aerobic amoeba well known for its ability to transform from an amoeba to a flagellate form. The genome of N. gruberi has been recently published, and in silico predictions demonstrated that Naegleria has the capacity for both aerobic respiration and anaerobic biochemistry to produce molecular hydrogen in its mitochondria. This finding was conside...